Wednesday, December 14, 2022


Cancer Genomics
9:30-10:20Stephen Chanock, NIH | The genomic profile of papillary thyroid carcinoma after the Chernobyl accident in 1986 & how ionizing radiation actually causes cancer
10:20-10:40Gidi Rechavi, Sheba | Cancer Epitranscriptomics
10:40-11:00Shai Izraeli, TAU | From Down Syndrome to high risk leukemia
11:00-11:20Yosi Maruvka, Technion | Tumors with mismatch repair deficiency: biology, detection and prevention
11:20-11:35Itamar Simon, HUJI | Both Cell Autonomous And Non-Autonomous Processes Modulate The Association Between Replication Timing And Mutation Rate
11:35-13:00Poster session & lunch
Precision Medicine
13:00-13:20Nir Friedman, HUJI | Subtyping of small cell lung cancer using plasma cell-free nucleosomes
13:20-13:40Ron Shamir, TAU | Computational analysis of large scale cancer multi-omic data
13:40-14:00Binyamin Knisbacher, BIU | The CLL-map project: from multi-omics to precision medicine in a common leukemia
14:00-14:20Dvir Aran, IIT | Deep-phenotyping of single-cells for precision medicine
14:20-14:35Rani Elkon, TAU | Evaluation of European-based polygenic risk score for breast cancer on Ashkenazi Jewish women in Israel
14:35-14:50Ofir Raz, WIS | Cancer Evolution Diagnosis Using Cell Lineage Reconstruction Based on Somatic Mutations in Short Tandem Repeats
14:50-15:30Coffee break
15:30-16:20Hannah Carter, UCSD | The influence of genetic background on anti-tumor immune response
16:20-16:40Yardena Samuels, WIS | Revisiting the neoantigen approach to cancer immunotherapy
16:40-17:00Yuval Shaked, IIT | A holistic approach to study biomarkers to predict immunotherapy outcomes
17:00-17:20Keren Yizhak, IIT | Estimating tumor mutational burden from RNA-seq without a matched-normal sample


Thursday, December 15, 2022


Tumor Microenvironment
9:30-10:20Nick Haining, ArsenalBio | Engineering the fate and function T cells for cancer therapy
10:20-10:40Shai Shen-Orr, IIT | Modeling cancer progression
10:40-11:00Leeat Keren, WIS | Unraveling the tumor microenvironment by multiplexed imaging
11:00-11:20Neta Erez, TAU | Stromal and immune plasticity shape the metastatic microenvironment
11:20-11:40Asaf Madi | Immune niches, the preprinted version
11:40-13:30Poster session & lunch
Cancer Cells
13:30-13:50Noam Shomron, TAU | DNA and RNA as insights for precision medicine
13:50-14:10Ofir Cohen, BGU | From intractable many to manageable few – evolutionary convergence of drug-resistant cell-states in metastatic breast cancer
14:10-14:30Uri Ben-David, TAU | Genomic approaches for identifying vulnerabilities of aneuploid cells
14:30-14:50Yaara Oren, TAU | Beyond Darwin: understanding cancer persister cells
14:50-15:05Matan Hofree, HUJI | Tissue level insights from cellular measurements – Identifying multi-cellular hubs in colorectal cancer
15:05-15:20Juman Jurban, BGU | Characterizing genomic properties that shape cancer aneuploidy landscapes by applying machine learning methods
15:20-16:00Coffee break
16:00-16:50Gad Getz, Broad institute | Leveraging convergent evolution to discover mechanisms of resistance to cancer therapy
16:50-17:15Summary and poster winners


Poster Division to Dates


Poster Presenters
Elad Zisman | Alternative Splicing and Expression Dynamics in T Cells
Hagay Ladany | Developing preventive cancer vaccine for lynch syndrome
Yaniv Eyal-Lubling | Exploring clonal plasticity in breast tumour xenografts by integration of single-cell transcriptional profiles with inferred genomic clones
Roy Granit | Exploring the immune-tumor microenvironment and tertiary lymphoid structures using high resolution single-cell spatial transcriptomics
Roy Granit | Gene model correction for PVRIG and TIGIT in single cell sequencing data enables accurate detection and study of its functional relevance
Neta Nevo | Identification of Driver Proteins for Accelerating Human Immune Recovery Post Chemotherapy
Oren Barboy | Modeling the dynamics of T cell response to immunotherapy facilitates optimization of combinatorial treatment protocols
Or Livne | Prediction model for immunotherapy response based on RNA derived biomarkers
Daniel Gurevich | The distinct features of the chromosomal unstable tumors compared to genomic stable tumors
Ofir Shorer | The role of tumor and immune metabolism in cancer patient response to immune checkpoint blockade therapy
Gaia Frant | Unique features of the human mismatch repair pathway
Roni Keshet | Using bacterial genomic information as biomarkers for predicting patients’ response to immunotherapy


Poster Presenter
Artem Danilevsky | Adaptive sequencing using nanopores and deep learning of mitochondrial DNA
Michael Mints | Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
Rony Chanoch-Myers | Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
Noam Galili | Exploring glioma organization and heterogeneity through spatial transcriptomics
Sagi Gordon | Identification of chemo-resistance mechanisms and survival markers in pediatric ewing sarcoma tumors using MS-based clinical proteomics
Ron Sheinin | Identification of factors mediating the signaling convergence of multiple receptors following cell-cell interaction
Edo Dotan | Multiple sequence alignment as a sequenceto-sequence lerning problem
Avishay Spitzer | Response of glioma to standard-of-care treatment dissected at single-cell resolution
Sapir Levin | The role of hematopoietic progenitor cells in immunotherapy resistance
Barak Davidi | Ultrasound surveillance of small incidentally detected gallbladder polyps: projected benefits by age, sex, and comorbidity level
Zachary Levine | Unraveling the genetic mechanisms behind novel complex phenotypes from the israeli 10K cohort
Almog Angel | xCell 2.0: a generic tool for cell-type enrichment analysis that enables prediction of response to immunotherapies


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